Identification and potential clinical applications of novel autophagy/mitophagy proteins in the biofluids of Alzheimer’s disease published in prestigious Ageing Research Reviews (IF=12.5, Q1, D1) by Jianying Zhang, He-Ling Wang, Kateřina Veverová, Martin Vyhnálek and Evandro Fei Fang. https://doi.org/10.1016/j.arr.2024.102378

Congratulations to all MitAD members!

Highlights

• •Elevated PINK1 and reduced TFEB in CSF and serum samples of AD patients.
• •Correlations were found between levels of PINK1, TFEB, and clinical indicators of AD.
• •Changes of the fluid protein levels of mitophagy/autophagy proteins could be developed into markers in assisting diagnsosi and prognosis.