Dedicated to the project

Hou, Y., Chu, X., Park, J.-H., Zhu, Q., Hussain, M., Li, Z., Madsen, H. B., Yang, B., Wei, Y., Wang, Y., Fang, E. F., Croteau, D. L., & Bohr, V. A. (2024). Urolithin A improves Alzheimer’s disease cognition and restores mitophagy and lysosomal functions. Alzheimer’s & Dementia: The Journal of the Alzheimer’s Association, 20(6), 4212–4233. https://doi.org/10.1002/alz.13847

Zhang, J., Wang, H.-L., Veverova, K., Vyhnalek, M., & Fang, E. F. (2024). Identification and potential clinical applications of novel autophagy/mitophagy proteins in the biofluids of Alzheimer’s disease patients. Ageing Research Reviews. https://doi.org/10.1016/j.arr.2024.102378

Veverová K, Laczó J, Katonová A, Horáková H, Matušková V, Angelucci F, Laczó M, Nedelská Z, Hort J, Wang HL, Zhang J, Shi L, Fei Fang E, Vyhnálek M. (2024). Alterations of human CSF and serum-based mitophagy biomarkers in the continuum of Alzheimer disease. Autophagy. 1-11. doi: 10.1080/15548627.2024.2340408. 

Caponio D, Veverova K, Zhang S, Shi L, Wong G, Vyhnalek M, Fang EF (2022). Compromised autophagy and mitophagy in brain ageing and Alzheimer’s diseases, Aging Brain 2, doi.org/10.1016/j.nbas.2022.100056

Vyhnalek M, Jester DJ, Andel R, Horakova H, Nikolai T, Laczó J, Matuskova V, Cechova K, Sheardova K, Hort J. (2022). Contribution of Memory Tests to Early Identification of Conversion from Amnestic Mild Cognitive Impairment to Dementia. J Alzheimers Dis. 88(4):1397-1409. doi: 10.3233/JAD-215364

Aman, Y., Schmauck-Medina, T., Hansen, M. …,& Fang, E. F. (2021). Autophagy in healthy aging and disease. Nat Aging 1, 634–650. DOI: https://doi.org/10.1038/s43587-021-00098-4

Xie, C., Aman, Y., Frank, J., Donate-Lagartos, M. J., Gudmundsrud, R., Cechova, K., Liu, S., Vyhnalek, M., & Fang, E. F. (2021). Autophagic processes in early- and late-onset Alzheimer’s disease. In Autophagy in Health and Disease 2. Beverly Rothermel, Abhinav Diwan, eds. Academic Press, 287-299., ISBN 9780128220030

Previously published

AMAN, Y., SCHMAUCK-MEDINA, T., HANSEN, M., MORIMOTO, R.I., SIMON, A.K., BJEDOV, I., PALIKARAS, K., SIMONSEN, A., JOHANSEN, T., TAVERNARAKIS, N., RUBINSZTEIN, D.C., PARTRIDGE, L., KROEMER, G., LABBADIA, J., FANG, E.F., 2021. Autophagy in healthy aging and disease. Nat. Aging 18 1, 634–650., DOI: https://doi.org/10.1038/s43587-021-00098-4

XIE C, AMAN Y, ADRIAANSE BA, CADER MZ, PLUN-FAVREAU H, XIAO J, FANG EF (2020) Culprit or Bystander: Defective Mitophagy in Alzheimer’s Disease. Front. Cell Dev. Biol. 7,. DOI: 10.3389/fcell.2019.00391

LACZÓ J, CECHOVA K, PARIZKOVA M, LERCH O, ANDEL R, MATOSKA V, KAPLAN V, MATUSKOVA V, NEDELSKA Z, VYHNALEK M, HORT J (2020) The Combined Effect of APOE and BDNF Val66Met Polymorphisms on Spatial Navigation in Older Adults. J. Alzheimer’s Dis. 78, 1473–1492. DOI: 10.3233/JAD-200615

CECHOVA K, ANDEL R, ANGELUCCI F, CHMATALOVA Z, MARKOVA H, LACZÓ J, VYHNALEK M, MATOSKA V, KAPLAN V, NEDELSKA Z, WARD DD, HORT J (2020) Impact of APOE and BDNF Val66Met Gene Polymorphisms on Cognitive Functions in Patients with Amnestic Mild Cognitive Impairment. J. Alzheimer’s Dis. 73, 247–259. DOI: 10.3233/JAD-190464

FANG EF, HOU Y, PALIKARAS K, ADRIAANSE BA, KERR JS, YANG B, LAUTRUP S, HASAN-OLIVE MM, CAPONIO D, DAN X, ROCKTÄSCHEL P, CROTEAU DL, AKBARI M, GREIG NH, FLADBY T, NILSEN H, CADER MZ, MATTSON MP, TAVERNARAKIS N, BOHR VA (2019) Mitophagy inhibits amyloid-β and tau pathology and reverses cognitive deficits in models of Alzheimer’s disease. Nat. Neurosci. 22, 401–412. DOI: 10.1038/s41593-018-0332-9

MARKOVA H, NIKOLAI T, MAZANCOVA AF, CECHOVA K, SHEARDOVA K, GEORGI H, KOPECEK M, LACZÓ J, HORT J, VYHNALEK M (2019) Differences in Subjective Cognitive Complaints Between Non-Demented Older Adults from a Memory Clinic and the Community. J. Alzheimer’s Dis. 70, 61–73. DOI: 10.3233/JAD-180630

COUGHLAN G, LACZÓ J, HORT J, MINIHANE A-M, HORNBERGER M (2018) Spatial navigation deficits — overlooked cognitive marker for preclinical Alzheimer disease? Nat. Rev. Neurol. 14, 496–506. DOI: 10.1038/s41582-018-0031-x